Rh Factor: Genetics, Clinical Importance, and Future Perspectives
The Rh factor, also known as the Rhesus factor, is an important antigen found on the surface of red blood cells. It plays a crucial role in blood transfusion compatibility…
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Naranjo Algorithm for Causality Assessment of Adverse Drug Reactions (ADR)
The Naranjo Algorithm, developed in 1981 by Naranjo et al., is a structured, questionnaire-based tool used to assess the probability that a drug caused an adverse drug reaction (ADR). It…
Methods in Causality Assessment
Introduction to Causality assessment Causality assessment is a critical process in pharmacovigilance aimed at determining whether a specific drug is responsible for an observed adverse drug reaction (ADR). It helps…
Detection and Reporting of ADR
Adverse Drug Reactions Adverse Drug Reactions (ADRs) are an essential aspect of drug safety monitoring and are critical for ensuring the safe use of medicines. According to the World Health…
Determination of Erythrocyte Sedimentation Rate (ESR)
Aim: Determination of Erythrocyte Sedimentation Rate (ESR) References: 1. Bull, B. S., & Brecher, G. (2005). Clinical Hematology: Principles, Procedures, Correlations. Lippincott Williams & Wilkins. 2. Lewis, S. M., Bain,…
Determination of pA₂ Value of Prazosin Using Rat Anococcygeus Muscle (Schild Plot Method)
Aim: Determination of pA₂ Value of Prazosin Using Rat Anococcygeus Muscle (Schild Plot Method) References 1. Arunlakshana, O., & Schild, H.O. (1959). Some quantitative uses of drug antagonists. British Journal…
Bioassay of Serotonin Using Rat Fundus Strip by Three-Point Bioassay
Aim: Bioassay of Serotonin Using Rat Fundus Strip by Three-Point Bioassay References 1. Ghosh, M.N. (2008). Fundamentals of Experimental Pharmacology (6th ed.). Hilton & Company. 2. Rang, H.P., Dale, M.M.,…
In process and final product quality control tests for capsules
1. In-Process Quality Control (IPQC) Tests for Capsules In-process quality control tests are performed during different stages of manufacturing to monitor the product and ensure consistency. These tests help in…
Filling, finishing and special techniques of formulation of hard gelatin capsules, manufacturing defects
Hard gelatin capsules are a popular solid dosage form, consisting of two parts: a body and a cap. These capsules are primarily composed of gelatin, which acts as the capsule…
Capsule Sizes: An In-Depth Guide
Capsule Sizes: Capsules are a common dosage form in pharmaceuticals, offering flexibility for delivering various active ingredients. Capsules come in a range of sizes to accommodate different dosages, allowing pharmaceutical…
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