Vitamin B12 Deficiency

Megaloblastic Anemia: Pathophysiology

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Megaloblastic anemia is a type of anemia characterized by the presence of abnormally large, immature red blood cells (megaloblasts) in the bone marrow and peripheral blood. This condition primarily results from deficiencies in vitamin B12 (cobalamin) and/or folic acid (vitamin B9). These vitamins are crucial for DNA synthesis and red blood cell production. This note … Read more

Megaloblastic Anemia

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Megaloblastic anemia is a type of macrocytic anemia characterized by the presence of unusually large and immature red blood cells (megaloblasts) in the bone marrow. This condition is primarily caused by a deficiency of vitamin B12 or folic acid, which are essential for DNA synthesis and normal maturation of red blood cells. Etiopathogenesis The main … Read more