Preclinical evaluation phase

The preclinical evaluation phase is a critical stage in drug development that occurs before testing in human subjects. It involves a comprehensive assessment of the safety, pharmacokinetics, pharmacodynamics, and toxicology of a potential drug candidate using in vitro and in vivo models. Here’s a detailed note on the preclinical evaluation phase: 1. Study Design and … Read more

Pharmacodynamics: Introduction, Concepts and applications

1. Introduction to Pharmacodynamics Pharmacodynamics (PD) is the branch of pharmacology that focuses on the effects of drugs on the body, including the mechanisms of action, the relationship between drug concentration and effect, and the factors influencing the drug’s response. In essence, pharmacodynamics seeks to answer the question: What does the drug do to the … Read more

General Pharmacology: Definition, Historical Landmarks and Scope

Pharmacology is the branch of biomedical science that deals with the study of drugs and their interactions with living organisms. It encompasses a wide range of topics, from the identification and characterization of pharmacologically active compounds to the understanding of their mechanisms of action and the effects they produce in the body. Pharmacology is a … Read more

Scope of Biochemistry in Pharmacy

Biochemistry plays a pivotal role in pharmacy, serving as a cornerstone for understanding the molecular basis of drug action, metabolism, and therapeutic interventions. Integrating biochemistry into pharmacy practice broadens the scope and impact of pharmaceutical sciences. Here’s a glimpse into the significant contributions of biochemistry to the pharmacy domain: 1. Drug Discovery and Design Biochemical … Read more

Introduction to Pharmacology

Pharmacology is the scientific discipline that focuses on the study of drugs and their effects on living organisms. It plays a crucial role in the field of medicine, as it encompasses the study of how drugs interact with biological systems, the mechanisms of drug action, and their therapeutic and toxic effects. The word “pharmacology” is … Read more