Regulation of Enzymes: Enzyme Induction, Repression, and Allosteric Regulation

Regulation of Enzymes The regulation of enzyme activity is critical for maintaining cellular homeostasis and responding to environmental changes. Enzymes are regulated through various mechanisms to ensure that metabolic pathways function efficiently and adaptively. This note covers enzyme induction and repression, as well as the regulation of allosteric enzymes. Enzyme Induction and Repression Enzyme Induction … Read more

Enzyme Induction and Enzyme Inhibition

Enzyme Induction and Enzyme Inhibition: In the field of pharmacology, understanding the mechanisms that regulate drug metabolism is of paramount importance. Drug metabolism governs the pharmacokinetics of a drug—how it is absorbed, distributed, metabolized, and excreted (ADME)—and therefore has a direct influence on its therapeutic efficacy and potential toxicity. The liver is the principal organ … Read more