ICH Guidelines: Purpose, Participants, and Process

Screenshot 2025 10 18 121230 ICH Guidelines: Purpose, Participants, and Process

1. Introduction The pharmaceutical industry is one of the most regulated industries worldwide. Medicines and medical products must be safe, effective, and of high quality before reaching the public. To achieve these goals across diverse regions and regulatory frameworks, a unified approach to drug development and approval is essential. Historically, drug manufacturers had to fulfill … Read more

Introduction to Autacoids and Classification of Histamine

Screenshot 2025 10 02 153613 Introduction to Autacoids and Classification of Histamine

Introduction to Autacoids The word autacoid originates from the Greek words “autos” (self) and “akos” (remedy or healing). Literally, autacoids mean “self-remedy” or “self-healing” substances. In pharmacology, autacoids are defined as biologically active chemical substances produced by the body that exert local effects, generally close to the site of their synthesis, and are subsequently metabolized … Read more

Parenteral Products: Production Procedure, Production etc

Screenshot 2025 10 02 143655 Parenteral Products: Production Procedure, Production etc

1. Introduction Parenteral products are sterile preparations intended for administration by injection, infusion, or implantation into the human or animal body. Unlike oral formulations, they bypass the gastrointestinal tract and enter directly into the systemic circulation or localized tissues. Because of this, sterility, pyrogen-free status, particulate-free nature, isotonicity, and safety are critical quality attributes. Parenterals … Read more

Parenteral Products: Definition, Types, Advantages, and Limitations

Screenshot 2025 10 02 131013 Parenteral Products: Definition, Types, Advantages, and Limitations

Parenteral products are sterile pharmaceutical preparations intended for administration by injection, infusion, or implantation into the body. These products bypass the gastrointestinal tract, making them essential for patients who cannot take medications orally due to various medical conditions. The term “parenteral” is derived from the Greek words para (beside) and enteron (intestine), meaning that the … Read more

International Conference on Frontiers in Pharma

📅 Date: 29th – 30th September 2025 📍 Venue: F2 Auditorium, Amity University Uttar Pradesh, Noida, India About the Conference The pharmaceutical industry is currently witnessing a paradigm shift driven by technological innovation, artificial intelligence (AI), nano-engineering, and genomics. To explore these exciting frontiers, Amity Institute of Pharmacy, Amity University Uttar Pradesh (AUUP), with the … Read more

Artemis Hospitals, Gurgaon Job

Greetings from Artemis Hospitals! Artemis Hospitals, Gurgaon, a flagship healthcare institution renowned for its excellence in patient care and advanced medical practices, is expanding its team of highly skilled professionals. We invite passionate, committed, and qualified nursing professionals to join us in our mission of delivering world-class healthcare with compassion, precision, and integrity. At Artemis, … Read more

Penicillins: Chemical Degradation and SAR

Screenshot 2025 08 19 110557 Penicillins: Chemical Degradation and SAR

Chemical degradation of penicillins involves various reactions that can occur under different conditions, leading to the loss of their pharmacological activity. 1. Acid Hydrolysis: Mechanism: Penicillins are susceptible to acid hydrolysis, where the β-lactam ring is opened, leading to inactive degradation products. Conditions: Acid hydrolysis occurs in acidic environments, such as the stomach or acidic … Read more

Penicillins

Penicillins

Penicillin, the most important antibiotic, was first extracted from the mould Penicillium notatum. Subsequently, a mutant of a related mould, P. chrysogenum, was found to give the highest yield of penicillin and is employed for the commercial production of this antibiotic. Penicillin belongs to a group of antibiotics called β-lactam antibiotics. The basic structure of … Read more

β-Lactam antibiotics

β-Lactam antibiotics

Beta-lactam antibiotics are a class of antibiotics characterized by the presence of a beta-lactam ring in their molecular structure. This ring is crucial for its antibacterial activity as it interferes with the synthesis of bacterial cell walls, ultimately leading to bacterial cell death. Beta-lactam antibiotics are generally well-tolerated but can cause allergic reactions in some … Read more