Explore Pharmaceutical Inorganic Chemistry with clear, exam-oriented notes covering limit tests, electrolytes, essential inorganic pharmaceuticals, assays, principles, and applications in pharmacy education and practice.
Oral Rehydration Salt (ORS) is a vital medical intervention used to treat dehydration, particularly in cases of diarrheal illnesses. This comprehensive overview delves into the composition, uses, preparation, and significance of ORS in maintaining health, especially in regions prone to waterborne diseases. 1. Composition of ORS A carefully balanced electrolyte solution, known as ORS, replaces … Read more
Assay of Calcium Gluconate Assaying calcium gluconate involves determining its purity and concentration. This is typically done through various analytical techniques, including titration, spectroscopy, and chromatography. 1. Titration: Titrate calcium gluconate with a standardized solution of a complexing agent, such as EDTA (ethylenediaminetetraacetic acid). Determine the endpoint of the titration through a color change, and … Read more
Potassium chloride is a vital chemical compound with a range of applications in various fields, including medicine, agriculture, and industry. This comprehensive overview delves into the properties, uses, and significance of potassium chloride. 1. Chemical Composition Chemical Formula: KCl Molecular Weight: 74.55 g/mol 2. Physical Properties Appearance: Potassium chloride is a white crystalline or granular … Read more
Assay of Sodium Chloride Assaying sodium chloride involves determining its purity and concentration, typically by titration or gravimetric analysis. 1. Titration: To assay sodium chloride using titration, react a solution of sodium chloride with a solution of silver nitrate (AgNO3), forming insoluble silver chloride (AgCl). Calculate the concentration of sodium chloride by determining the amount … Read more
Electrolyte replacement therapy is a fundamental aspect of medical treatment, aiming to correct imbalances in essential ions within the body. This comprehensive examination delves into the various electrolytes used in replacement therapy, their significance, and their roles in restoring health and homeostasis. 1. Sodium (Na+) Significance: Sodium is a vital extracellular cation, essential for osmoregulation, … Read more
Physiological ions, including cations and anions, play pivotal roles in various bodily functions. They are essential for maintaining the integrity of biological systems, regulating cellular processes, and ensuring overall health. This comprehensive overview delves into the functions of major physiological ions, highlighting their significance and roles in human physiology. 1. Sodium (Na+) Significance: Sodium is … Read more
Electrolytes are ions with essential roles in maintaining various physiological functions in the human body. They are categorized into extracellular and intracellular electrolytes, each playing distinct roles. This comprehensive overview explores the major extracellular and intracellular electrolytes, their significance, distribution, and physiological functions. 1. Extracellular Electrolytes 1.1. Sodium (Na+) Significance: Sodium is the primary cation … Read more
Isotonicity, the property of a solution having the same osmotic pressure as bodily fluids, is essential in various medical, pharmaceutical, and biological applications. This comprehensive overview delves into the calculations and methods employed to measure isotonicity and adjust solutions to achieve this crucial property. 1. Isotonic Solutions Defined – Isotonic solutions have the same … Read more
Tonicity, in the context of solutions, refers to the effective osmotic pressure exerted across a semipermeable membrane by solute particles within the solution. It is a crucial parameter in various fields, including medicine, pharmacology, and biology. This comprehensive examination explores the diverse methods and techniques used to measure tonicity, highlighting their significance and applications. 1. … Read more
Buffered isotonic solutions are a class of liquid formulations used in various medical, pharmaceutical, and healthcare applications. These solutions serve critical roles in maintaining physiological balance, ensuring compatibility with biological systems, and enabling safe and effective drug delivery. In this comprehensive exploration, we delve into the intricacies of buffered isotonic solutions, their composition, significance, and … Read more
