Drug distribution

Drug distribution is a fundamental pharmacokinetic process that follows drug absorption. It involves the movement of a drug throughout the body once it has entered the systemic circulation. The bloodstream distributes the drug to various tissues and organs, and this distribution can impact the drug’s concentration at the site of action, as well as its … Read more

Bioavailability

Bioavailability is a pharmacokinetic term that describes the fraction of an administered drug that reaches the systemic circulation in an unchanged form and is available to produce a pharmacological effect. In other words, it measures how a drug is absorbed and becomes available in the bloodstream, both in terms of extent and rate. Bioavailability typically … Read more

Drug absorption

Drug absorption is a crucial pharmacokinetic process that refers to the movement of a drug from its site of administration into the bloodstream. It is the first step in a drug’s journey through the body and plays a significant role in determining the drug’s effectiveness and onset of action. Here are the key aspects of … Read more

Vaginal route

The vaginal route of drug administration involves the introduction of medications into the vagina. This route is mainly used for gynecological and reproductive health purposes and has specific advantages and disadvantages. Here are the key points related to the vaginal route of drug administration: Advantages 1. Local and Systemic Therapy: The vaginal route offers versatility … Read more

Rectal route

The rectal route of drug administration involves the insertion of medications into the rectum, typically in the form of suppositories or enemas. This route has its advantages and disadvantages and is used for various clinical purposes. Here are the key points related to the rectal route of drug administration: Advantages 1. Bypass First-Pass Metabolism Rectal … Read more

Inhalation route

The inhalation route of drug administration involves the introduction of medications directly into the respiratory system, typically via inhalation devices or nebulizers. This route is used primarily for respiratory medications but can also be employed for systemic drug delivery in some cases. Here are the key points related to the inhalation route of drug administration: … Read more

Transdermal route

The transdermal drug administration route involves applying medications in the form of patches or topical preparations directly onto the skin’s surface. The drugs are absorbed through the skin and into the bloodstream, providing a controlled, steady release of the medication. This route offers several advantages and disadvantages, making it particularly useful for specific types of … Read more

Topical route

The topical route of drug administration involves applying medications directly to the skin or mucous membranes, such as the eyes, nose, ears, or genital areas. This route has several advantages and disadvantages and is commonly used for dermatological, ophthalmic, and otic (ear) medications. Here are the key points related to the topical route of drug … Read more

Subcutaneous (SC) route

The subcutaneous (SC) route of drug administration involves injecting medications into the subcutaneous tissue, which is the layer of tissue just beneath the skin. This route is used for various medications and has specific advantages and disadvantages. Here are the key points related to the subcutaneous route of drug administration: Advantages 1. Slower Absorption: Subcutaneous … Read more

Intramuscular (IM) route

The intramuscular (IM) route of drug administration involves delivering medications into the muscle tissue using a hypodermic needle. This route has its own advantages and disadvantages and is commonly used for specific medications and clinical situations. Here are the key points related to the intramuscular route of drug administration: Advantages 1. Sustained Drug Release The … Read more